Advances in DNA Repair by Sonya Vengrova

April 3, 2017 | Anatomy | By admin | 0 Comments

By Sonya Vengrova

During the last a long time, nice advances were made in knowing the mobile DNA fix pathways. even as, a wealth of descriptive wisdom of human illnesses has been gathered. Now, the fundamental learn of the mechanisms of DNA fix is merging with scientific learn, putting the motion of the DNA fix pathways within the context of the complete organism. Such integrative process permits knowing of the illness mechanisms and is priceless in enhancing diagnostics and prevention, in addition to designing higher remedies. This booklet highlights the important function of DNA fix in human health and wellbeing and health and wellbeing. The studies offered right here, comprise exact descriptions of DNA fix pathways, in addition to research of a big physique of facts addressing hyperlinks among DNA harm fix and human health and wellbeing. they are going to be of curiosity to a wide viewers, from molecular biologists engaged on DNA fix in any version process, to clinical researchers.

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Global analysis of the core cell cycle regulators of Arabidopsis identifies novel genes, reveals multiple and highly specific profiles of expression and provides a coherent model for plant cell cycle con‐ trol. The Plant Journal 2005; 41(4) 546–566. x. , Schnittger A. Molecular control and function of endorepli‐ cation in development and physiology. Trends in Plant Science 2012; 16(11) 624–634. 001. J. Endoreplication and polyploidy: insights into development and disease. Development 2013; 140(1) 3–12.

C. Plant Mitochondrial Genome Evolution Can Be Explained by DNA repair mechanisms. Genome biology and evolution 2013; 5(6) 1079–1086. 1093/gbe/evt069. , Kühn K. DNA-binding proteins in plant mitochondria: Implications for transcription. Mitochondrion. 2014; in press. 004. C. Genes and junk in plant mitochondria-repair mechanisms and se‐ lection. Genome Biology and Evolution 2014; 6(6) 1448–1453. 1093/gbe/evu115. , Chen J. DNA damage tolerance: a double-edged sword guarding the ge‐ nome. Translational research: the journal of laboratory and clinical medicine 2013; 2(3) 107–129.

2013; 22(4) 839–848. 1007/s11248-013-9690-y. , Hirt H. New insights into an old story: Agrobacterium-induced tumor formation in plants by plant transformation. The EMBO Journal 2010; 29(6) 1021–32. 8. I. Ku80 plays a role in non-homologous recombination but is not required for T-DNA integration in Arabidopsis. The Plant Journal 2003; 35(5) 557–565. 1365-313X. x. , Tzfira T. Involvement of KU80 in T-DNA integration in plant cells. Proceedings of the National Academy of Scien‐ ces of the United States of America 2005; 102(52) 19231–19236.

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