By Yashwant Pathak, Simon Benita
Chapter 1 Antibody?Mediated Drug supply structures: normal overview and purposes (pages 1–12): Navdeep Kaur, Karthikeyan Subramani and Yashwant Pathak
Chapter 2 Immunoliposomes for Cardiovascular focusing on (pages 13–33): Tatyana Levchenko, William Hartner and Vladimir P. Torchilin
Chapter three Antibody?Mediated Drug supply structures for Breast melanoma Therapeutics (pages 35–55): Leonor Munoz Alcivar and Yashwant Pathak
Chapter four improvement of Immunonconjugates for in Vivo supply: melanoma prognosis, Imaging, and treatment (pages 57–81): Arutselvan Natarajan
Chapter five Mathematical types of Anti?TNF remedies and their Correlation with Tuberculosis (pages 83–104): Simeone Marino, Mohammad Fallahi?Sichani, Jennifer J. Linderman and Denise E. Kirschner
Chapter 6 certain Nanoparticles in Radiotherapy (pages 105–128): Misty Muscarella and Yashwant Pathak
Chapter 7 Electrically?Enhanced supply of substances and Conjugates for melanoma remedy (pages 129–143): Arutselvan Natarajan, Luca Campana and Raji Sundararajan
Chapter eight Characterization of Monoclonal Antibody editions and Glycosylation (pages 145–167): Ting Zheng, Srinivasa Rao, Jeff Rohrer and Chris Pohl
Chapter nine Antibody?Mediated Drug supply process for Lymphatic focusing on therapy (pages 169–190): Fang Wu, Hong Ding and Zhirong Zhang
Chapter 10 equipment for Nanoparticle Conjugation to Monoclonal Antibodies (pages 191–207): Junling Li and Chin okay. Ng
Chapter eleven Single?Use structures in Animal Cell–Based Bioproduction (pages 209–228): William G. Whitford
Chapter 12 Immunoliposomes for particular Drug supply (pages 229–266): Manuela Calin
Chapter thirteen Gene remedy concentrating on Kidney illnesses: Routes and automobiles (pages 267–277): Yoshitaka Isaka, Yoshitsugu Takabatake and Hiromi Rakugi
Chapter 14 Detection of Antibodies to Poly(Ethylene Glycol) Polymers utilizing Double?Antigen?Bridging Immunogenicity ELISA (pages 279–290): Yijuan Liu, Helen Reidler, Jing Pan, David Milunic, Dujie Qin, Dave Chen, Yli Remo Vallejo and Ray Yin
Chapter 15 Antibodies in Nanomedicine and Microimaging equipment (pages 291–349): Rakesh Sharma
Chapter sixteen equipment for Polymeric Nanoparticle Conjugation to Monoclonal Antibodies (pages 351–363): Uyen Minh Le, Hieu Tran and Yashwant Pathak
Chapter 17 Plant?Derived Antibodies for educational, business, and healing purposes (pages 365–381): Slavko Komarnytsky and Nikolai Borisjuk
Chapter 18 Monoclonal Antibodies as Biopharmaceuticals (pages 383–389): Girish J. Kotwal
Chapter 19 Pulmonary concentrating on of Nanoparticles and Monoclonal Antibodies (pages 391–405): Weiyuan Chang
Chapter 20 Antibody?Mediated Arthritis and New healing Avenues (pages 407–426): Kutty Selva Nandakumar
Chapter 21 Immunonanoparticles for Nuclear Imaging and Radiotherapy (pages 427–456): Oren Giladi and Simon Benita
Chapter 22 Monoclonal Antibodies within the remedy of bronchial asthma (pages 457–472): Glenn J. Whelan
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Additional info for Antibody-Mediated Drug Delivery Systems: Concepts, Technology, and Applications
2% Hybridomas Insect Insectcells cells E. coli 10 S. coli, has been omitted since Pfizer stopped its marketing in January 2008. CHAPTER 18, FIGURE 2 See text for full caption. 650 700 O N N OH HO N N O HO H O N H OH S O N H H N N O OH N N S N S OH O N N H O OH OH O N H O OH O OH N N N N O (A) OH O OH (B) CHAPTER 21, FIGURE 1 Means of radioisotope delivery using (A) mAb and (B) a mAb-targeted NP. (A) (B) (C) CHAPTER 21, FIGURE 3 (A) Transaxial CT, (B) PET, and (C) fused image from a patient with a large clear-cell renal carcinoma.
2 immunoliposomes bind to human bronchial epithelial cells (BEAS-2B) and human umbilical vein endothelial cells (HUVECs) in a speciﬁc dose- and time-dependent manner . As discovered recently, both the quantity of expressed adhesion molecules and the distribution of binding sites on the surface of endothelial cells play a role in the targeting process. Lipid rafts have received increasing attention as cellular membrane organelles contributing to the pathogenesis of several structural and functional TABLE 1 Immunoliposomes in Cardiovascular Targetinga Antibody Attached to Liposomes Antimyosin Antiﬁbrinogen Anti-ICAM-1 Anti-VCAM-1 Anti-E-selectin Action Model Ref.
1). It is also important to determine how long such a protective effect can last. Therefore, to determine whether antimyosin immunoliposomes could protect severely injured conditions for 1 to 5 days , the cell viability of cardiocytes cultured under hypoxic conditions was determined in the presence of plain or immunoliposomes. 8%, respectively. These data show that the protective effect can lead to long-term preservation of cardiocyte viability, which should be especially important from a practical point of view for extended preservation of myocardial viability.