By Evert C. A. Kaal MD, Charles J. Vecht MD,PhD (auth.), David Schiff MD, Santosh Kesari MD, PhD, Patrick Y. Wen MD (eds.)
From the stories of the 1st Edition…
"…provides an exceptional evaluation and advent to the administration of neurological problems of melanoma. good equipped and succinct, you possibly can find and make the most of information…" – Neurology
"…an very important source for the clinical oncologist, within the prognosis and remedy of many neurological stipulations because of melanoma… This ebook is unique and is suggested for clinical oncologists and radiotherapists, who will locate it an invaluable advisor to facing the neurological difficulties encountered in melanoma patients." – Annals of Oncology
"The editors and members are to be congratulated for generating a well timed and entire textual content of this speedily evolving box. I strongly suggest melanoma Neurology in scientific perform for neurologists, together with neuro-oncologists… the sensible nature and transparent presentation of the textual content make the knowledge very obtainable to these in neurosurgery, scientific and radiation oncology, neuropathology, and neuroradiology." – Annals of Neurology
From the Foreword to the 1st Edition…
This e-book offers a entire research of ways melanoma impacts the apprehensive approach… It encompasses the adventure of senior physicians actively engaged in neuro-oncology facilities in the course of the international… The large scope of this e-book will entice physicians who're now not experts, yet who wish an up to date reference on all points of neuro-oncology. – Jerome Posner, MD, Memorial Sloan-Kettering melanoma heart, big apple, NY
Neuro-oncology has advanced considerably as a medical and learn self-discipline during the last few a long time. melanoma Neurology in scientific perform: Neurologic problems of melanoma and its therapy, moment variation offers clinicians from quite a few backgrounds and degrees of educating with a connection with aid concentration the differential analysis, remedy procedure, and administration plan for the melanoma sufferer with neurologic indicators and findings.
The quantity starts with an summary of the sector of neuro-oncology and a evaluation of the position of neuroimaging within the analysis of neuro-oncologic affliction. numerous chapters on interpretation and administration of universal neuro-oncologic signs stick to. next sections comprise chapters at the direct and oblique neurologic issues of melanoma in addition to problems of treatment. the ultimate part makes a speciality of the spectrum and administration of neurologic affliction in sufferers with melanoma of particular organs.
Cancer Neurology in medical perform: Neurologic problems of melanoma and its therapy, moment version is a vital new paintings that goals to develop and deepen the familiarity of clinicians with the variety and administration of neuro-oncologic illnesses so one can enhance the standard of take care of melanoma patients.
Read or Download Cancer Neurology In Clinical Practice: Neurologic Complications of Cancer and Its Treatment PDF
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Additional info for Cancer Neurology In Clinical Practice: Neurologic Complications of Cancer and Its Treatment
An extended search for the extent of systemic tumor prior to establishing a histopathologic diagnosis can lead to an inappropriate expenditure of resources, including unnecessary imaging studies and longer interval to diagnostic biopsy. Staging examinations are appropriate for patients with a systemic malignancy but are inappropriate for most patients with primary brain tumors. In the ideal situation, a decision regarding biopsy site selection would be made quickly after the identification of a brain mass based on a rationally chosen set of diagnostic studies, and the procedure scheduled immediately thereafter.
Specifically, in neoplasms the restricted diffusion results from dense cellularity, whereas in cerebral abscess the restricted diffusion results from mucopurulent contents of the lesion. Therefore, in brain tumors the restricted diffusion tends to colocalize with the area of nodular contrast enhancement and the central nonenhancing portion of the lesion shows elevated diffusion (Fig. 4). In abscess, the central nonenhancing component shows restricted diffusion. These findings apply to abscesses caused by bacterial and fungal organisms, but not to those from toxoplasmosis, where restricted diffusion is not common.
As a consequence, overall more than 50% of patients with gliomas experience recurrent seizures during the course of their disease, while 11% of patients with brain metastases and 19% of patients with neoplastic meningitis suffer recurrent seizures during their substantially shorter lifetimes (6,22). Low-grade tumors may be more refractory than higher-grade lesions (6). Seizures that develop late in the clinical course are typically more responsive to treatment than those that occur early (9). Seizures that are initially controlled but return at the time of tumor recurrence are also relatively refractory to treatment (147).